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Musk briefly loses the job of world’s richest man

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December 8, 2022

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Musk briefly loses the job of world’s richest man

Elon Musk

Elon Musk briefly lost his position as the world’s richest person on Wednesday to LVMH CEO Bernard Arnault, whose family owns the luxury brand Louis Vuitton.

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According to Forbes, at 3:30 p.m. ET on Wednesday, Arnault surpassed Musk to become the world’s richest person with an estimated $184.7 billion, but when US markets closed at 4:00 p.m. ET, Musk was back. to the top with $185.4 billion.

Jeff Bezos

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On September 27, 2021, Musk overtook Amazon’s Jeff Bezos to become the world’s richest person for the first time.

Gautam Adani

Bezos has since fallen to fourth with $111.3 billion, while Indian businessman Gautam Adani ranks third with $134.8 billion.

Musk’s main source of wealth is Tesla, whose shares peaked at $320 billion in November 2021 after car rental giant Hertz announced a large order from the maker of electric vehicles.

But in 2022, Tesla’s shares are down nearly 50 percent.

Also in October

Also in October 2022, the billionaire acquired the social media platform Twitter, for $44 billion.

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$Ronna McDaniel will serve a rare fourth term as chair of the Republican National Committee emerging victorious in a contentious bid for reelection DANA POINT Calif Ronna McDaniel will serve a rare fourth term as chair of the Republican National Committee emerging victorious in a contentious bid for reelection McDaniel on Friday defeated her main challenger the RNC s California national committeewoman Harmeet Dhillon by a vote of 111 committee members to 51 MyPillow CEO Mike Lindell whose campaign drew little support received four votes The at times fierce two month long race sparked debates about how the RNC has managed its finances and fared in recent elections It also saw some members on both sides of the contest publicly calling into question the character of their colleagues putting McDaniel and her allies on the defensive and forcing the incumbent chair to assemble an aggressive whip operation to shore up her support We need all of us McDaniel told committee members after calling Dhillon and Lindell to join her onstage We heard you grassroots We know We heard Harmeet we heard Mike Lindell W ith us united and all of us joining together the Democrats are going to hear us in 2024 Speaking to a swarm of reporters after the vote Dhillon said she is committed to working toward repairing fractures in the party but that party unity won t come overnight We did not expect this to become a national grassroots movement she said So I m committed to healing and coming together with folks but at the end of the day if our party is perceived as totally out of touch with the grassroots which I think some may take away from this outcome we have some work to do The committee meeting at the Waldorf Astoria Monarch Beach a luxury seaside resort illustrated the tense division within the Republican ranks that continue to exist months after the 2022 elections Dhillon whose firm represents former President Donald Trump raised her profile over the last year with regular appearances on Fox News evening programs garnering support in her bid for chair from a prominent cast of conservative commentators That list included Tucker Carlson Laura Ingraham and Charlie Kirk who helped mobilize an army of grassroots activists to call and email RNC committee members urging them to oppose McDaniel s reelection But those high profile figures were not always a value add On multiple occasions on the fence members told Dhillon and her allies that they would be open to supporting her if Kirk weren t one of her surrogates said Oscar Brock the national committeeman from Tennessee who was part of her team Dhillon had assured concerned members that Kirk a firebrand conservative figure wouldn t be part of RNC staff should she win But there was never a conversation among her whip team about asking Kirk to dial down his support There probably should have been Brock said But there wasn t In an interview Friday Kirk called McDaniel s victory a direct insult to the grassroots people that they send 10 emails a day to begging for money I think the RNC is going to have a lot of trouble raising small dollar donations a lot of trouble rebuilding trust Kirk said Going into 2024 the apparatus that should be a machine and clicking on all cylinders and firing on all cylinders is going to be in a trust deficit Kirk wasn t the only Dhillon ally whose aggressive advocacy ended up turning off members of the committee Caroline Wren who most recently ran Kari Lake s gubernatorial campaign in Arizona got into a heated exchange with Georgia state Rep Vernon Jones on Thursday night in the lobby of the Waldorf Astoria According to three people familiar with the confrontation Wren who has been Dhillon s top adviser in her campaign for chair told Jones Everyone knows you re here fucking whipping votes for Ronna She proceeded to call him a fucking sell out adding that the grassroots will never support you again A person familiar with the conversation said Wren had also approached Jones two other times this week once while he was speaking with an RNC member during which she called him the fucking enemy and another time as Jones was speaking with Lake during which she called him a sellout Wren confirmed she was frustrated with Jones because he had previously been a public supporter of Dhillon But she downplayed the tenor of Thursday night s conversation saying she did not use profanity and adding that she even laughed at one point Asked Friday about the encounter Jones smiled and shrugged saying there s not much more to say In addition to relying on prominent conservative figures Dhillon s whip team also held calls once or twice weekly said Brock But several committee members in recent days said that calls and emails from Dhillon s team had become too much eventually solidifying their support for McDaniel I think Harmeet could have taken a different approach and said The RNC it isn t where we want to be And here s what it will be like when I become chair without you know calling into question the motives of all the people that are a part of the organization said Paul Dame the Vermont Republican Party chair who joined the committee in fall 2021 After remaining undecided for much of the chair race Dame put his support behind McDaniel this week Dhillon drew a last minute nod of support from Ron DeSantis on Thursday though it s unclear whether it swayed any votes The Florida governor s decision to weigh in on the race stood in contrast to Trump Despite choosing McDaniel as his RNC chair after his 2016 victory the former president publicly stayed out of this year s contest though Dhillon said he sent her a text message through one of his advisers on Wednesday In the text Trump joked about disliking one of her endorsers she declined to say who Prior to that message Dhillon hadn t spoken with the former president since shortly after she announced her chair bid She said that when she told Trump she was running he remarked that McDaniel had also announced a campaign He said OK well that ll be interesting Dhillon recalled Good luck Despite calling for wholesale reforms to the party moving forward Dhillon declined on Friday to answer whether she supports Republicans moving on from Trump in 2024 saying it was inappropriate for an RNC committee member to influence voters in the primary process While Trump stayed mum his top aides were privately supporting McDaniel s reelection bid though advisers Chris LaCivita and Susie Wiles disputed the notion that they were whipping votes for her while meeting with members at the Waldorf Astoria in recent days Ultimately McDaniel s team with the help of allies convinced members that a fourth term was earned even after the lackluster midterms It left Dhillon s supporters exasperated Ya got me said Bill Palatucci the national committee member from New Jersey about why his colleagues on the committee overwhelmingly backed McDaniel despite multiple cycles of GOP disappointments That has been my speech to these people on email and via phone calls and meetings here We just had this terrible midterm cycle and you guys don t want to make a change For whatever reason they have their heads buried in the sand McDaniel s bid for a fourth term was a fight before it officially started Former Rep Lee Zeldin the GOP gubernatorial nominee in New York whose race drew national attention for being closer than expected floated his name for RNC chair shortly after the midterms He received one write in vote on Friday And Palatucci upset by what he described as McDaniel s brief disaster of a call with RNC members on Nov 9 emailed top RNC staff and some members his concerns In the note he wrote that McDaniel s remarks showed incredible unwillingness to face the reality of what happened last evening adding that he and other members want a real honest assessment of what happened When she formally announced her bid on Nov 14 McDaniel held a lengthy call with members taking questions and making her case for why she should continue in the role McDaniel had previously told members in 2021 she would not seek another term after her third By the end of the week McDaniel had assembled a list of more than 100 members publicly supporting her Just after Thanksgiving she announced she was launching a Republican Party Advisory Council to review the party s electoral performance in 2022 Last week McDaniel sent members a document she called her Vision for Unity which included plans to improve Republicans legal ballot collecting efforts find new tactics for small dollar fundraising that has suffered in recent years and boosting the youth vote In the document first reported by POLITICO McDaniel made an appeal to members who were inclined to support Dhillon saying she would work with Dhillon and Lindell over the next two years in an effort to unite all corners of the GOP I look forward to uniting once again as a Party and working together alongside Harmeet and Mike to heal as a Party and elect Republicans McDaniel wrote The event at the Waldorf Astoria drew an assortment of Republican officials from Lake and Jones to former Arkansas Gov Asa Hutchinson a likely 2024 presidential contender who could be seen meeting with reporters in the hotel lobby on Wednesday and Thursday Former Secretary of State Mike Pompeo another presidential hopeful though he did not attend the meeting left stacks of his new book on a check in table for attendees Former Alaska Gov Sarah Palin made an appearance Friday morning posing for photos with attendees before an RNC security guard at one point asked to see her credential lanyard Credit https www politico com news 2023 01 27 ronna mcdaniel wins her race for rnc chair 00079980$
Ronna McDaniel wins RNC chair race that grew very messy by the end

$Ronna McDaniel will serve a rare fourth term as chair of the Republican National Committee emerging victorious in a contentious bid for reelection DANA POINT Calif Ronna McDaniel will serve a rare fourth term as chair of the Republican National Committee emerging victorious in a contentious bid for reelection McDaniel on Friday defeated her main challenger the RNC s California national committeewoman Harmeet Dhillon by a vote of 111 committee members to 51 MyPillow CEO Mike Lindell whose campaign drew little support received four votes The at times fierce two month long race sparked debates about how the RNC has managed its finances and fared in recent elections It also saw some members on both sides of the contest publicly calling into question the character of their colleagues putting McDaniel and her allies on the defensive and forcing the incumbent chair to assemble an aggressive whip operation to shore up her support We need all of us McDaniel told committee members after calling Dhillon and Lindell to join her onstage We heard you grassroots We know We heard Harmeet we heard Mike Lindell W ith us united and all of us joining together the Democrats are going to hear us in 2024 Speaking to a swarm of reporters after the vote Dhillon said she is committed to working toward repairing fractures in the party but that party unity won t come overnight We did not expect this to become a national grassroots movement she said So I m committed to healing and coming together with folks but at the end of the day if our party is perceived as totally out of touch with the grassroots which I think some may take away from this outcome we have some work to do The committee meeting at the Waldorf Astoria Monarch Beach a luxury seaside resort illustrated the tense division within the Republican ranks that continue to exist months after the 2022 elections Dhillon whose firm represents former President Donald Trump raised her profile over the last year with regular appearances on Fox News evening programs garnering support in her bid for chair from a prominent cast of conservative commentators That list included Tucker Carlson Laura Ingraham and Charlie Kirk who helped mobilize an army of grassroots activists to call and email RNC committee members urging them to oppose McDaniel s reelection But those high profile figures were not always a value add On multiple occasions on the fence members told Dhillon and her allies that they would be open to supporting her if Kirk weren t one of her surrogates said Oscar Brock the national committeeman from Tennessee who was part of her team Dhillon had assured concerned members that Kirk a firebrand conservative figure wouldn t be part of RNC staff should she win But there was never a conversation among her whip team about asking Kirk to dial down his support There probably should have been Brock said But there wasn t In an interview Friday Kirk called McDaniel s victory a direct insult to the grassroots people that they send 10 emails a day to begging for money I think the RNC is going to have a lot of trouble raising small dollar donations a lot of trouble rebuilding trust Kirk said Going into 2024 the apparatus that should be a machine and clicking on all cylinders and firing on all cylinders is going to be in a trust deficit Kirk wasn t the only Dhillon ally whose aggressive advocacy ended up turning off members of the committee Caroline Wren who most recently ran Kari Lake s gubernatorial campaign in Arizona got into a heated exchange with Georgia state Rep Vernon Jones on Thursday night in the lobby of the Waldorf Astoria According to three people familiar with the confrontation Wren who has been Dhillon s top adviser in her campaign for chair told Jones Everyone knows you re here fucking whipping votes for Ronna She proceeded to call him a fucking sell out adding that the grassroots will never support you again A person familiar with the conversation said Wren had also approached Jones two other times this week once while he was speaking with an RNC member during which she called him the fucking enemy and another time as Jones was speaking with Lake during which she called him a sellout Wren confirmed she was frustrated with Jones because he had previously been a public supporter of Dhillon But she downplayed the tenor of Thursday night s conversation saying she did not use profanity and adding that she even laughed at one point Asked Friday about the encounter Jones smiled and shrugged saying there s not much more to say In addition to relying on prominent conservative figures Dhillon s whip team also held calls once or twice weekly said Brock But several committee members in recent days said that calls and emails from Dhillon s team had become too much eventually solidifying their support for McDaniel I think Harmeet could have taken a different approach and said The RNC it isn t where we want to be And here s what it will be like when I become chair without you know calling into question the motives of all the people that are a part of the organization said Paul Dame the Vermont Republican Party chair who joined the committee in fall 2021 After remaining undecided for much of the chair race Dame put his support behind McDaniel this week Dhillon drew a last minute nod of support from Ron DeSantis on Thursday though it s unclear whether it swayed any votes The Florida governor s decision to weigh in on the race stood in contrast to Trump Despite choosing McDaniel as his RNC chair after his 2016 victory the former president publicly stayed out of this year s contest though Dhillon said he sent her a text message through one of his advisers on Wednesday In the text Trump joked about disliking one of her endorsers she declined to say who Prior to that message Dhillon hadn t spoken with the former president since shortly after she announced her chair bid She said that when she told Trump she was running he remarked that McDaniel had also announced a campaign He said OK well that ll be interesting Dhillon recalled Good luck Despite calling for wholesale reforms to the party moving forward Dhillon declined on Friday to answer whether she supports Republicans moving on from Trump in 2024 saying it was inappropriate for an RNC committee member to influence voters in the primary process While Trump stayed mum his top aides were privately supporting McDaniel s reelection bid though advisers Chris LaCivita and Susie Wiles disputed the notion that they were whipping votes for her while meeting with members at the Waldorf Astoria in recent days Ultimately McDaniel s team with the help of allies convinced members that a fourth term was earned even after the lackluster midterms It left Dhillon s supporters exasperated Ya got me said Bill Palatucci the national committee member from New Jersey about why his colleagues on the committee overwhelmingly backed McDaniel despite multiple cycles of GOP disappointments That has been my speech to these people on email and via phone calls and meetings here We just had this terrible midterm cycle and you guys don t want to make a change For whatever reason they have their heads buried in the sand McDaniel s bid for a fourth term was a fight before it officially started Former Rep Lee Zeldin the GOP gubernatorial nominee in New York whose race drew national attention for being closer than expected floated his name for RNC chair shortly after the midterms He received one write in vote on Friday And Palatucci upset by what he described as McDaniel s brief disaster of a call with RNC members on Nov 9 emailed top RNC staff and some members his concerns In the note he wrote that McDaniel s remarks showed incredible unwillingness to face the reality of what happened last evening adding that he and other members want a real honest assessment of what happened When she formally announced her bid on Nov 14 McDaniel held a lengthy call with members taking questions and making her case for why she should continue in the role McDaniel had previously told members in 2021 she would not seek another term after her third By the end of the week McDaniel had assembled a list of more than 100 members publicly supporting her Just after Thanksgiving she announced she was launching a Republican Party Advisory Council to review the party s electoral performance in 2022 Last week McDaniel sent members a document she called her Vision for Unity which included plans to improve Republicans legal ballot collecting efforts find new tactics for small dollar fundraising that has suffered in recent years and boosting the youth vote In the document first reported by POLITICO McDaniel made an appeal to members who were inclined to support Dhillon saying she would work with Dhillon and Lindell over the next two years in an effort to unite all corners of the GOP I look forward to uniting once again as a Party and working together alongside Harmeet and Mike to heal as a Party and elect Republicans McDaniel wrote The event at the Waldorf Astoria drew an assortment of Republican officials from Lake and Jones to former Arkansas Gov Asa Hutchinson a likely 2024 presidential contender who could be seen meeting with reporters in the hotel lobby on Wednesday and Thursday Former Secretary of State Mike Pompeo another presidential hopeful though he did not attend the meeting left stacks of his new book on a check in table for attendees Former Alaska Gov Sarah Palin made an appearance Friday morning posing for photos with attendees before an RNC security guard at one point asked to see her credential lanyard Credit https www politico com news 2023 01 27 ronna mcdaniel wins her race for rnc chair 00079980$
Ronna McDaniel wins RNC chair race that grew very messy by the end

Ronna McDaniel wins RNC chair race that grew very messy by the end

GOP Chair Ronna McDaniel wins party leadership vote

GOP Chair Ronna McDaniel wins party leadership vote

GOP Chair Ronna McDaniel wins party leadership vote

Intel stock tumbles after brutal results

Intel stock tumbles after brutal results

Intel stock tumbles after brutal results

$Pfizer has laid off employees at its La Jolla CA and Groton CT sites according to multiple LinkedIn posts from former employees The Big Pharma confirmed to Endpoints News it has let go some employees but a spokesperson declined to specify how many workers were impacted and the exact locations affected Earlier this month the drug developer had confirmed to Endpoints it was sharpening its focus and doing away with some early research on areas such as rare disease oncology and gene therapies Unlock this article along with other benefits by subscribing to one of our paid plans George Scangos one of the all time great biotech CEOs says the time has come to turn over the reins one last time The 74 year old biotech legend spent close to three decades in a CEO post The first was at Exelixis which is still heavily focused on a drug Scangos advanced in the clinic The second retirement was at Biogen where he and his team were credited with a big turnaround with the now fading MS blockbuster Tecfidera And the third comes at Vir where he traded in his Big Biotech credentials for a marquee founder s role back on the West Coast hammering out a Covid 19 alliance with Hal Barron then R amp D chief at GSK and breaking new ground on infectious diseases with some high powered venture players Unlock this article along with other benefits by subscribing to one of our paid plans J amp J and Legend Biotech s next step in turning their CAR T therapy Carvykti into a potential megablockbuster has succeeded the companies said Friday Carvykti achieved the primary endpoint progression free survival in an open label Phase III study testing the treatment in second to fourth line multiple myeloma patients The CARTITUDE 4 trial for which there aren t any hard data yet represents the biggest development for Carvykti s ability to compete with Bristol Myers Squibb s Abecma since its approval last February A 13 year old Dutch biotech is going through a liquidation process after an unexpected end to its Phase III trial testing whether its combination of two monoclonal antibodies was superior to Incyte s Jakafi Xenikos had hoped to prove its investigational therapy named T Guard was better than Jakafi at garnering a complete response in patients experiencing life threatening complications in which new cells from a hematopoietic stem cell transplant begin to fight the body Jakafi was approved for the indication steroid refractory acute graft versus host disease in May 2019 Unlock this story instantly and join 157 400 biopharma pros reading Endpoints daily and it s free The FDA s Vaccines and Related Biological Products Advisory Committee VRBPAC voted unanimously in favor of harmonizing Covid vaccine compositions meaning all current vaccine recipients would receive a bivalent vaccine regardless of whether they ve gotten their primary series The vote marks an effort to clear up confusion around varying formulations and dosing schedules for current primary series and booster vaccines as well as get closer to the strains that are circulating according to committee member Paul Offit professor of pediatrics at the Children s Hospital of Philadelphia Last July Jeanne Loring stood on a dirt road surrounded by Florida swampland and watched as a nearby SpaceX rocket blasted into the sky The payload included a very personal belonging cell clusters mimicking parts of her brain For more than two decades Loring has been at the forefront of a stem cell field that always seems on the brink of becoming the next thing in medicine but has been slow to lift off Unlock this article along with other benefits by subscribing to one of our paid plans Israeli biotech Sol Gel Technologies announced Friday that it got its hands on a rare disease drug candidate from PellePharm for almost 75 million amid claims that the drug has the potential to reach a 300 million market Execs said on a conference call Friday morning that patidegib a hedgehog signaling pathway blocker is being investigated to treat Gorlin syndrome a rare genetic disorder that increases the risk of of developing certain kinds of cancer such as basal cell skin cancer and medulloblastoma a type of brain cancer The disease affects around one in every 31 000 people and an estimated 70 000 people worldwide Sana Biotechnology is finally headed to the clinic Thursday afternoon the biotech announced the FDA had cleared its application to start a clinical trial for its allogeneic or off the shelf CAR T cell therapy targeting the antigen CD19 for patients with B cell lymphomas and leukemias Sana said its therapy dubbed SC291 was designed to evade the immune system which could help cell therapy produce a more durable response in patients a concern that has followed such off the shelf therapies that use donor cells as opposed to a patient s own cells Unlock this story instantly and join 157 400 biopharma pros reading Endpoints daily and it s free BeiGene CEO John Oyler and Endpoints News Executive Editor Drew Armstrong spoke one on one about where the drugmaker is headed in its quest to become a diversified multinational and what it will take to get there This transcript has been edited for brevity and clarity I am joined today by BeiGene CEO John Oyler By way of introduction John and I met about a little over three years ago for the first time in Beijing when I was doing some reporting I got to travel around the country and I had this huge notebook full of reporting on interesting things that his company was doing and some of the other companies were doing over there And I came back to the states ready to write a great magazine story about BeiGene and about innovation that was happening globally And then I think we all know what happened about a week and a half after I returned in January of 2020 And unfortunately that work never saw the light of day Unlock this article along with other benefits by subscribing to one of our paid plans The FDA hasn t detected any potential safety signals including for stroke in people aged 65 years and older who have received Pfizer s bivalent Covid booster one senior official told members of the agency s Vaccines and Related Biological Products Advisory Committee VRBPAC on Thursday The update comes as the FDA and CDC investigate a preliminary signal that may indicate an increased risk of ischemic stroke in older Americans who received Pfizer s updated shot If you re already an Endpoints subscriber enter your email below for a magic link that lets you log in quickly without using a password Please note the magic link is one time use only and expires after 24 hours We ll e mail you a link to set a new password Please note this link is one time use only and is valid for only 24 hours Credit https endpts com pfizer lays off employees at california and connecticut sites nbsp nbsp nbsp$
Pfizer lays off employees at California and Connecticut sites

$Pfizer has laid off employees at its La Jolla CA and Groton CT sites according to multiple LinkedIn posts from former employees The Big Pharma confirmed to Endpoints News it has let go some employees but a spokesperson declined to specify how many workers were impacted and the exact locations affected Earlier this month the drug developer had confirmed to Endpoints it was sharpening its focus and doing away with some early research on areas such as rare disease oncology and gene therapies Unlock this article along with other benefits by subscribing to one of our paid plans George Scangos one of the all time great biotech CEOs says the time has come to turn over the reins one last time The 74 year old biotech legend spent close to three decades in a CEO post The first was at Exelixis which is still heavily focused on a drug Scangos advanced in the clinic The second retirement was at Biogen where he and his team were credited with a big turnaround with the now fading MS blockbuster Tecfidera And the third comes at Vir where he traded in his Big Biotech credentials for a marquee founder s role back on the West Coast hammering out a Covid 19 alliance with Hal Barron then R amp D chief at GSK and breaking new ground on infectious diseases with some high powered venture players Unlock this article along with other benefits by subscribing to one of our paid plans J amp J and Legend Biotech s next step in turning their CAR T therapy Carvykti into a potential megablockbuster has succeeded the companies said Friday Carvykti achieved the primary endpoint progression free survival in an open label Phase III study testing the treatment in second to fourth line multiple myeloma patients The CARTITUDE 4 trial for which there aren t any hard data yet represents the biggest development for Carvykti s ability to compete with Bristol Myers Squibb s Abecma since its approval last February A 13 year old Dutch biotech is going through a liquidation process after an unexpected end to its Phase III trial testing whether its combination of two monoclonal antibodies was superior to Incyte s Jakafi Xenikos had hoped to prove its investigational therapy named T Guard was better than Jakafi at garnering a complete response in patients experiencing life threatening complications in which new cells from a hematopoietic stem cell transplant begin to fight the body Jakafi was approved for the indication steroid refractory acute graft versus host disease in May 2019 Unlock this story instantly and join 157 400 biopharma pros reading Endpoints daily and it s free The FDA s Vaccines and Related Biological Products Advisory Committee VRBPAC voted unanimously in favor of harmonizing Covid vaccine compositions meaning all current vaccine recipients would receive a bivalent vaccine regardless of whether they ve gotten their primary series The vote marks an effort to clear up confusion around varying formulations and dosing schedules for current primary series and booster vaccines as well as get closer to the strains that are circulating according to committee member Paul Offit professor of pediatrics at the Children s Hospital of Philadelphia Last July Jeanne Loring stood on a dirt road surrounded by Florida swampland and watched as a nearby SpaceX rocket blasted into the sky The payload included a very personal belonging cell clusters mimicking parts of her brain For more than two decades Loring has been at the forefront of a stem cell field that always seems on the brink of becoming the next thing in medicine but has been slow to lift off Unlock this article along with other benefits by subscribing to one of our paid plans Israeli biotech Sol Gel Technologies announced Friday that it got its hands on a rare disease drug candidate from PellePharm for almost 75 million amid claims that the drug has the potential to reach a 300 million market Execs said on a conference call Friday morning that patidegib a hedgehog signaling pathway blocker is being investigated to treat Gorlin syndrome a rare genetic disorder that increases the risk of of developing certain kinds of cancer such as basal cell skin cancer and medulloblastoma a type of brain cancer The disease affects around one in every 31 000 people and an estimated 70 000 people worldwide Sana Biotechnology is finally headed to the clinic Thursday afternoon the biotech announced the FDA had cleared its application to start a clinical trial for its allogeneic or off the shelf CAR T cell therapy targeting the antigen CD19 for patients with B cell lymphomas and leukemias Sana said its therapy dubbed SC291 was designed to evade the immune system which could help cell therapy produce a more durable response in patients a concern that has followed such off the shelf therapies that use donor cells as opposed to a patient s own cells Unlock this story instantly and join 157 400 biopharma pros reading Endpoints daily and it s free BeiGene CEO John Oyler and Endpoints News Executive Editor Drew Armstrong spoke one on one about where the drugmaker is headed in its quest to become a diversified multinational and what it will take to get there This transcript has been edited for brevity and clarity I am joined today by BeiGene CEO John Oyler By way of introduction John and I met about a little over three years ago for the first time in Beijing when I was doing some reporting I got to travel around the country and I had this huge notebook full of reporting on interesting things that his company was doing and some of the other companies were doing over there And I came back to the states ready to write a great magazine story about BeiGene and about innovation that was happening globally And then I think we all know what happened about a week and a half after I returned in January of 2020 And unfortunately that work never saw the light of day Unlock this article along with other benefits by subscribing to one of our paid plans The FDA hasn t detected any potential safety signals including for stroke in people aged 65 years and older who have received Pfizer s bivalent Covid booster one senior official told members of the agency s Vaccines and Related Biological Products Advisory Committee VRBPAC on Thursday The update comes as the FDA and CDC investigate a preliminary signal that may indicate an increased risk of ischemic stroke in older Americans who received Pfizer s updated shot If you re already an Endpoints subscriber enter your email below for a magic link that lets you log in quickly without using a password Please note the magic link is one time use only and expires after 24 hours We ll e mail you a link to set a new password Please note this link is one time use only and is valid for only 24 hours Credit https endpts com pfizer lays off employees at california and connecticut sites nbsp nbsp nbsp$
Pfizer lays off employees at California and Connecticut sites

Pfizer lays off employees at California and Connecticut sites

How Adeleke won, lost Osun election

How Adeleke won, lost Osun election

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Mega churches, schools bar old naira note payment, offering

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IGP recommends ex-PPRO Mba, Owohunwa as Ogun, Lagos CPs

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IGP recommends ex-PPRO Mba, Owohunwa as Ogun, Lagos CPs

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TSLA blasts through 4 resistance, 7.50 next up

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TSLA blasts through $154 resistance, $167.50 next up

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How to watch live, stream link, team news

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Emefiele shuns Reps, banks ration new notes

Emefiele shuns Reps, banks ration new notes

PDP Abia state governorship candidate don die

PDP Abia state governorship candidate don die

PDP Abia state governorship candidate don die

TSLA Jumps on Upbeat Demand Outlook

TSLA Jumps on Upbeat Demand Outlook

TSLA Jumps on Upbeat Demand Outlook

Tesla reports record revenue and beats on earnings

Tesla reports record revenue and beats on earnings

Tesla reports record revenue and beats on earnings

Tesla reports record profit but says prices must keep coming down

Tesla reports record profit but says prices must keep coming down

Tesla reports record profit but says prices must keep coming down

Deadline remains Jan 31 for old naira notes

Deadline remains Jan 31 for old naira notes

Deadline remains Jan 31 for old naira notes

‘Doomsday Clock’ moves to 90 seconds to midnight as nuclear threat rises

‘Doomsday Clock’ moves to 90 seconds to midnight as nuclear threat rises

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Microsoft offers lackluster guidance, says new business growth slowed in December

Microsoft offers lackluster guidance, says new business growth slowed in December

Microsoft offers lackluster guidance, says new business growth slowed in December

TSLA) Price Cuts Boosted Sales; Should You Buy the Stock?

TSLA) Price Cuts Boosted Sales; Should You Buy the Stock?

TSLA) Price Cuts Boosted Sales; Should You Buy the Stock?